Secondary Hemochromatosis

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Secondary hemochromatosis. I. Transfusion (exogenous) hemochromatosis.

(" bronszed diabetes ") is a condition of unknown etiology in which the body iron stores are vastly inscreased ansd in which there is portal cirrhosis of the liver. Diabetes, pigmenstation of the skins, and pan-creatic fibrosis are frequently, though not invariably, present. Numerous blood transsfusionss ins certain patienits have resulted ins the productions of a condition clinically somewhat ...

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Vulvar pruritus secondary to hemochromatosis

Background: While acute pruritus is often attributable to yeast vulvovaginitis, chronic pruritus can present as the result different conditions including manifestation of a systemic

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Hypoparathyroidism and Subclinical Hypothyroidism with Secondary Hemochromatosis

Hemochromatosis is an inherited genetic disorder of iron metabolism which can also occur as a secondary result of iron-overload. It leads to organ damage such as cardiomyopathy, liver cirrhosis, hypogonadism, and diabetes. This paper discusses a case of secondary hemochromatosis associated with repeated transfusions, presenting as asymptomatic hypoparathyroidism and subclinical hypothyroidism w...

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Secondary Hemochromatosis due to Chronic Oral Iron Supplementation

Iron may accumulate in excess due to a mutation in the HFE gene that upregulates absorption or when it is ingested or infused at levels that exceed the body's ability to clear it. Excess iron deposition in parenchymal tissue causes injury and ultimately organ dysfunction. Diabetes mellitus and hepatic cirrhosis due to pancreas and liver damage are just two examples of diseases that result from ...

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Experimental Hemochromatosis

In pernicious anemia and hemochromatosis an iron-containing pigment, hemosiderin, ordinarily derived from hemoglobin, is deposited in organs free from such pigment in most conditions that involve blood destruction. When sudden hemolysis takes place in a previously healthy human being, as after cutaneous burns or the action of a "blood poison," hemosiderin granules appear in the spleen, the red ...

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ژورنال

عنوان ژورنال: Blood

سال: 1953

ISSN: 0006-4971,1528-0020

DOI: 10.1182/blood.v8.9.837.837